Journal articles

  1. Itoyama T, Kawara M, Sugahara Y, Kurosawa D, Kawaguchi M, Fukui M, Skitamura SI, Nakayama K, Murakami Y. Nervous system disruption and swimming abnormality in early-hatched pufferfish (Takifugu niphobles) larvae caused by pyrene is independent of aryl hydrocarbon receptors. Marine Pollution Bulletin [in press].
  2. Kitamura SI, Akizuki M, Song JY, Nakayama K. Tributyltin exposure increases mortality of nodavirus infected Japanese medaka Oryzias latices larvae. Marine Pollution Bulletin [in press].
  3. Nakayama K, Yamashita R, Kitamura SI. Use of common carp (Cyprinus carpio) and Aeromonas salmonicida for detection of immunomodulatory effects of chemicals on fish. Marine Pollution Bulletin [in press].
  4. Chen K, Tsutsumi Y, Yoshitake S, Qiu X, Xu H, Hashiguchi Y, Honda M, Tashiro K, Nakayama K, Hano T, Suzuki N, Hayakawa K, Shimasaki Y, Oshima Y. 2017. Alteration of development and gene expression induced by ovo-nanoinjection of 3-hydroxybenzo[c]phenanthrene into Japanese medaka (Oryzias latipes) embryos. Aquatic Toxicology 182: 194–204.
  5. Tasaki J, Nakayama K, Shimizu I, Yamada H, Suzuki T, Nishiyama N, Yamane M. 2017. Cellular and molecular hypoxic response in common carp (Cyprinus carpio) exposed to linear alkylbenzene sulfonate (LAS) at sub-lethal concentrations. Environmental Toxicology 32: 122–130.
  6. Nakayama KSato K, Shibano T, Isobe T, Suzuki G, Kitamura SI. 2016. Occurrence of glucocorticoids discharged from a sewage treatment plant in Japan and the effects of clobetasol propionate exposure on the immune responses of common carp (Cyprinus carpio) to bacterial infection. Environmental Toxicology and Chemistry 35: 946–952.
  7. Kimura K, Okuda S, Nakayama K, Shikata T, Takahashi F, Yamaguchi H, Sakamoto S, Yamaguchi M, Tomaru Y. 2015. RNA sequencing revealed numerous polyketide synthase genes in the harmful dinoflagellate Karenia mikimotoi. PLOS ONE 10: e0142731.
  8. Kimura S, Nakayama K, Wada M, Kim U, Azumi K, Ojima T, Nozawa A, Kitamura SI, Hirose E. Cellulose is not degraded in the tunic of the edible ascidian Halocynthia roretzi contracting soft tunic syndrome. Diseases of Aquatic Organisms 116: 143–148.
  9. Suzuki G, Sato K, Isobe T, Takigami H, Brouwer A, Nakayama K. 2015. Detection of glucocorticoid receptor agonists in effluents from sewage treatment plants in Japan. Science of the Total Environment 527–528: 328–334.
  10. Isobe T, Sato K, Kim JW, Tanabe S, Suzuki G, Nakayama K. 2015. Determination of natural and synthetic glucocorticoids in effluent of sewage treatment plants using ultrahigh performance liquid chromatography-tandem mass spectrometry. Environmental Science and Pollution Research 22: 14127–14135.
  11. Sugahara Y, Kawaguchi M, Itoyama T, Kurokawa D, Tosa Y, Kitamura SI, Handoh IC, Nakayama K, Murakami Y. 2014. Pyrene induces a reduction in midbrain size and abnormal swimming behavior in early-hatched pufferfish larvae. Marine Pollution Bulletin 85: 479–486.
  12. Nakayama K, Inoue Y, Ikeda N, Hashizume N, Murakami H, Ishibashi T, Ikeda H, Isobe T, Kitamura SI, Suzuki G. 2014. Uptake and biological effects of synthetic glucocorticoids in common carp (Cyprinus carpio). Marine Pollution Bulletin 85: 370–375.
  13. Niimi S, Imoto M, Kunisue T, Watanabe MX, Kim E-Y, Nakayama K, Yasunaga G, Fujise Y, Tanabe S, Iwata H. 2014. Effects of persistent organochlorine exposure on the liver transcriptome of the common minke whale (Balaenoptera acutorostrata) from the North Pacific. Ecotoxicology and Environmental Safety 108: 95–105.
  14. Iwakiri S, Song JY, Nakayama K, Oh MJ, Ishida M, Kitamura SI. 2014. Host responses of Japanese flounder Paralichthys olivaceus with lymphocystis cell formation. Fish & Shellfish Immunology 38: 406–411.
  15. Uno S, Shintoyo A, Kokushi E, Yamamoto M, Nakayama K, Koyama J. 2012. Gas chromatography-mass spectrometry for metabolite profiling of Japanese medaka (Oryzias latipes) juveniles exposed to malathion. Environmental Science and Pollution Research 19: 2595–2605.
  16. Kawaguchi M, Sugahara Y, Watanabe T, Irie K, Ishida M, Kurokawa D, Kitamura SI, Tanaka H, Handoh IC, Nakayama K, Murakami Y. 2012. Nervous system disruption and concomitant behavioral abnormality in early-hatched pufferfish larvae exposed to heavy oil. Environmental Science and Pollution Research 19: 2488–2497.
  17. Song JY, Ohta S, Nakayama K, Murakami Y, Kitamura SI. 2012. A time-course study of immune response in Japanese flounder Paralichthys olivaceus exposed to heavy oil. Environmental Science and Pollution Research 19: 2300–2304.
  18. Song JY, Nakayama K, Kokushi E, Ito K, Uno S, Koyama J, Rahman MH, Murakami Y, Kitamura SI. 2012. Effect of heavy oil exposure on antibacterial activity and expression of immune-related genes in Japanese flounder Paralichthys olivaceus. Environmental Toxicology and Chemistry 31: 828–835.
  19. Irie K, Kawaguchi M, Mizuno K, Song JY, Nakayama K, Kitamura SI, Murakami Y. 2011. Effect of heavy oil on the development of the nervous system of floating and sinking teleost eggs. Marine Pollution Bulletin 63: 297–302.
  20. Song JY, Nakayama K, Murakami Y, Kitamura SI. 2011. Heavy oil exposure induces high mortalities in virus carrier Japanese flounder Paralichthys olivaceus. Marine Pollution Bulletin 63: 362–365.
  21. Kawaguchi M, Song JY, Irie K, Murakami Y, Nakayama K, Kitamura SI. 2011. Disruption of Sema3A expression causes abnormal neural projection in heavy oil exposed Japanese flounder larvae. Marine Pollution Bulletin 63: 356–361.
  22. Isobe T, Oshihoi T, Hamada H, Nakayama K, Yamada TK, Tajima Y, Amano M, Tanabe S. 2011. Contamination status of POPs and BFRs and relationship with parasitic infection in finless porpoises (Neophocaena phocaenoides) from Seto Inland sea and Omura bay, Japan. Marine Pollution Bulletin 63: 564–571.
  23. Nakayama K, Sei N, Handoh IC, Shimasaki Y, Honjo T, Oshima Y. 2011. Effects of polychlorinated biphenyls on liver function and sexual characteristics in Japanese medaka (Oryzias latipes). Marine Pollution Bulletin 63: 366–369.
  24. Hirakawa S, Imaeda D, Nakayama K, Udaka M, Kim E-Y, Kunisue T, Ogawa M, Matsuda T, Matsui S, Petrov EA, Batoev VB, Tanabe S, Iwata H. 2011. Integrative assessment of potential effects of dioxins and related compounds in wild Baikal seals (Pusa sibirica): Application of microarray and biochemical analyses. Aquatic Toxicology 105: 89–99.
  25. Nassef M, Tawaratsumita T, Oba Y, Satone H, Nakayama K, Shimasaki Y, Honjo T, Oshima Y. 2011. Induction of tributyltin-binding protein type 2 in Japanese flounder, Paralichthys olivaceus, by exposure to tributyltin-d27. Marine Pollution Bulletin 62: 412–414.
  26. Nassef M, Kato-Unoki Y, Furuta T, Nakayama K, Satone H, Shimasaki Y, Honjo T, Oshima Y. 2011. Molecular cloning, sequencing, and gene expression analysis of tributyltin-binding protein type 1 in Japanese medaka fish, Oryzias latipes. Zoological Science 28: 281–285.
  27. Nakayama K, Handoh IC, Kitamura S-I, Kim E-Y, Iwata H, Tanabe S. 2010. A microarray data analysis method to evaluate the impact of contaminants on wild animals. Science of the Total Environment 408: 5824–5827.
  28. Nakayama K, Matsudaira C, Tajima Y, Yamada TK, Yoshioka M, Isobe T, Takahashi S, Tanabe S. 2009. Temporal and spatial trends of organotin contamination in the livers of finless porpoises (Neophocaena phocaenoides) and their association with parasitic infection status. Science of the Total Environment 407: 6173–6178.
  29. Song J-Y, Sasaki K, Okada T, Kawakami H, Matsuoka S, Kang H-S, Nakayama K, Jung S-J, Oh M-J, Kitamura S-I. 2009. Antigenic differences of the scuticociliate Miamiensis avidus from Japan. Journal of Fish Diseases 32: 1027–1034.
  30. Nakayama K, Sakai H, Kitamura SI, Sudo A, Kim E-Y, Tanabe S, Iwata H. 2008. Comparison of gene expression profiles in the liver and cultured hepatic cells from wild common cormorants. Japanese Journal of Environmental Toxicology 11: 75–81 [in Japanese].
  31. Nakayama K, Iwata H, Tao L, Kannan K, Imoto M, Kim E-Y, Tashiro K, Tanabe S. 2008. Potential effects of perfluorinated compounds in common cormorants from Lake Biwa, Japan: an implication from the hepatic gene expression profiles by microarray. Environmental Toxicology and Chemistry 27: 2378–2386.
  32. Zhang X, Hecker M, Park J-W, Tompsett AR, Newsted J, Nakayama K, Jones PD, Au D, Kong R, Wu RSS, Giesy JP. 2008. Real time PCR array to study effects of chemicals on the hypothalamic-pituitary-gonadal axis of the Japanese medaka. Aquatic Toxicology 88: 173–182.
  33. Song J-Y, Nakayama K, Murakami Y, Jung S-J, Oh M-J, Matsuoka S, Kawakami H, Kitamura S-I. 2008. Does heavy oil pollution induce bacterial diseases in Japanese flounder Paralichthys olivaceus? Marine Pollution Bulletin 57: 889–894.
  34. Murakami Y, Kitamura S-I, Nakayama K, Matsuoka S, Sakaguchi H. 2008. Effects of heavy oil in the developing spotted halibut, Verasper variegates. Marine Pollution Bulletin 57: 524–528.
  35. Nakayama K, Sei N, Oshima Y, Tashiro K, Shimasaki Y, Honjo T. 2008. Alteration of gene expression profiles in the brain of Japanese medaka (Oryzias latipes) exposed to KC-400 or PCB126. Marine Pollution Bulletin 57: 460–466.
  36. Nakayama K, Kitamura S-I, Murakami Y, Song J-Y, Jung S-J, Oh M-J, Iwata H, Tanabe S. 2008. Toxicogenomic analysis of immune system-related genes in Japanese flounder (Paralichthys olivaceus) exposed to heavy oil. Marine Pollution Bulletin 57: 445–452.
  37. Shimasaki Y, Oshima Y, Inoue Y, Shibata H, Nakayama K, Inoue S, Imoto H, Kang I-J, Honjo T. 2008. Distribution of tributyltin in tissues of mature Japanese whiting, Sillago japonica and their eggs. Journal of Faculty of Agriculture, Kyushu University 53: 67–72.
  38. Nakayama K, Oshima Y, Tachibana T, Furuse M, Honjo T. 2007. Alteration of monoamine concentrations in the brain of medaka, Oryzias latipes, exposed to tributyltin. Environmental Toxicology 22: 53–57.
  39. Shimasaki Y, Oshima Y, Inoue S, Inoue Y, Kang I-J, Nakayama K, Imoto H, Honjo T. 2006. Effect of tributyltin on reproduction in Japanese whiting, Sillago japonica. Marine Environmental Research 62 (Suppl 1): S245–S248.
  40. Nakayama K, Iwata H, Kim E-Y, Tashiro K, Tanabe S. 2006. Gene expression profiling in common cormorant liver with an oligo array: assessing the potential toxic effects of environmental contaminants. Environmental Science & Technology 40: 1076–1083.
  41. Nakayama K, Oshima Y, Hiramatsu K, Shimasaki Y, Honjo T. 2005. Effects of polychlorinated biphenyls on the schooling behavior of Japanese medaka, Oryzias latipes. Environmental Toxicology & Chemistry 24: 2588–2593 .
  42. Nakayama K, Oshima Y, Nagafuchi K, Hano T, Shimasaki Y, Honjo T. 2005. Early–life-stage toxicity in offspring from exposed parent medaka, Oryzias latipes, to mixtures of tributyltin and polychlorinated biphenyls. Environmental Toxicology & Chemistry 24: 591–596.
  43. Oshima Y, Takeda T, Katayama S, Inoue Y, Inoue S, Nakayama K, Shimasaki Y, Honjo T. 2004. Relationship between temperature and pharmacokinetic parameters of florfenicol in carp (Cyprinus carpio). Japanese Journal of Environmental Toxicology 7: 61–68.
  44. Oshima Y, Koyama J, Nakayama K, Inoue Y, Shimasaki Y, Inoue S, Honjo T. 2004. Use of hepatic CYP1A1 activity in Japanese flounder to monitor oil dispersed from the Nakhodka spill. Japanese Journal of Environmental Toxicology 7: 123–129.
  45. Nakayama K, Oshima Y, Hiramatsu K, Honjo T. 2004. Alteration of general behavior of male medaka, Oryzias latipes, exposed to tributyltin and/or polychlorinated biphenyls. Journal of Faculty of Agriculture, Kyushu University 49: 85–92.
  46. Nakayama K, Oshima Y, Yamaguchi T, Tsuruda Y, Kang I-J, Kobayashi M, Imada N, Honjo T. 2004. Fertilization success and sexual behavior in male medaka, Oryzias latipes, exposed to tributyltin. Chemosphere 55: 1331–1337.
  47. Omura M, Shimasaki Y, Oshima Y, Nakayama K, Kubo K, Aou S, Ogata R, Hirata M, Inoue N. 2004. Distribution of tributyltin, dibutyltin and monobutyltin in the liver, brain and fat of rats: two-generation toxicity study of tributyltin chloride. Environmental Sciences 11: 123–132.
  48. Oshima Y, Kang I-J, Kobayashi M, Nakayama K, Imada N, Honjo T. 2003. Suppression of sexual behavior in male Japanese medaka (Oryzias latipes) exposed to 17beta-estradiol. Chemosphere 50: 429–436.